(Association for Assessment and Accreditation of Laboratory Animal Care International),
confirming\ncompliance with stringent animal welfare requirements,
international research standards, and high-quality
scientific output.<\/p>\n\n\n\n
![\"\"](\"http:\/\/centrummedycynyregeneracyjnej.pl\/wp-content\/uploads\/2025\/06\/ZW-MALA-1.jpg\")
<\/figure>\n\n\n\nInfrastructure and Animal Housing Conditions
The Small Animal Models Laboratory includes specialized rooms
designed for housing and conducting\nresearch on small laboratory animals,
such as mice, rats, and guinea pigs.
The facility is adapted for\nmaintaining animals and performing experiments in physiology,
nutrition, neurology, orthopedics,\nexperimental surgery, and translational research,
including toxicological and pharmacological studies.
Each room is designed to meet the species-specific needs of the animals,
ensuring optimal welfare\nconditions.
The laboratory is equipped with certified cages, environmental enrichment elements, and climate\nchambers
that allow precise management of living conditions.
Additional resources include inhalation\nanesthesia systems, surgical tables, two-photon microscopy,
luminescence chambers, and X-ray imaging.<\/p>\n\n\n\n
<\/p>\n\n\n\n
Environmental parameters \u2014 including temperature, humidity, and light cycles \u2014 are continuously
monitored and automatically regulated by an integrated Room Management System (RMS).
This ensures\nreproducible housing and experimental conditions,
which are essential for generating reliable scientific\nresults.<\/p>\n\n\n\n
Any deviations are immediately detected by an alarm system, The Laboratory also features a CO\u2082 chamber for humane euthanasia, an automatic cage washer, and a\nbedding exchange station, ensuring the highest standards of hygiene and biosecurity. <\/p>\n\n\n\n The key infrastructure of the Small Animal Models Laboratory includes: <\/p>\n\n\n\n Personnel and Animal Care <\/p>\n\n\n\n All research procedures are conducted following the 3Rs principle <\/p>\n\n\n\n Research Capabilities and Collaboration \u2022 Development of experimental models tailored to the project's requirements, <\/p>\n\n\n\n The Laboratory also integrates seamlessly with the Center for Translational Medicine\u2019s broader <\/p>\n\n\n\n Inquiries and collaboration proposals should be directed to: Laboratorium Ma\u0142ych Modeli Zwierz\u0119cych Centrum Medycyny Translacyjnej jestintegraln\u0105 cz\u0119\u015bci\u0105 nowoczesnej jednostki badawczej, specjalizuj\u0105cej si\u0119 w utrzymywaniu orazprowadzeniu zaawansowanych bada\u0144 na ma\u0142ych modelach zwierz\u0119cych, takich jak myszy,szczury i kawie domowe. Plac\u00f3wka zosta\u0142a zaprojektowana w celu zapewnieniaoptymalnych…<\/p>","protected":false},"author":2,"featured_media":513,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-432","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aktualnosci"],"_links":{"self":[{"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/posts\/432","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/comments?post=432"}],"version-history":[{"count":2,"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/posts\/432\/revisions"}],"predecessor-version":[{"id":517,"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/posts\/432\/revisions\/517"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/media\/513"}],"wp:attachment":[{"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/media?parent=432"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/categories?post=432"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/centrummedycynyregeneracyjnej.pl\/en\/wp-json\/wp\/v2\/tags?post=432"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
enabling rapid intervention.<\/p>\n\n\n\n![\"\"](\"http:\/\/centrummedycynyregeneracyjnej.pl\/wp-content\/uploads\/2025\/06\/ZW-MALA-2-1024x413.jpg\")
<\/figure>\n\n\n\n
Animals are kept in\nhigh-quality environments,
and their welfare is constantly monitored by
qualified personnel.<\/p>\n\n\n\n
wchodz\u0105:
4 climate chambers for housing mice, rats, and guinea pigs
(climate-controlled units, certified cages,\nenrichment elements),
CO\u2082 chamber for humane euthanasia,
Inhalation anesthesia device for rodents,
Surgical tables adapted for small models,
Bruker imaging chamber (X-ray and luminescence),
Integrated RMS monitoring and management system,
Automatic cage washer,
Bedding exchange station.<\/p>\n\n\n\n
Animal care at the Small Animal Models Laboratory is provided by
a qualified team of veterinarians with\nextensive clinical and research experience,
veterinary technicians, and laboratory animal caretakers.
All personnel are properly trained and certified
to work with laboratory animals, in accordance with the\nPolish Act of January 15, 2015,
on the protection of animals used for scientific or educational purposes.
The animals receive continuous veterinary care,
including clinical observation during acclimatization,
routine health monitoring during experiments, and medical support during post-procedural recovery.
Caretakers assess the animals' condition on an ongoing basis
and respond promptly to any signs of stress,\npain,
or compromised welfare through corrective measures.<\/p>\n\n\n\n
and in strict compliance with legal and\nethical standards.
Special attention is given to minimizing environmental and handling stress.
Animals are\nkept in socially compatible groups
with access to enrichment materials unless excluded
by the experimental\nprotocol.
This approach reduces stress and intra-group aggression.
The staff has in-depth knowledge of the physiology and behavior of mice,
rats, and guinea pigs, and they are\ntrained to detect
and promptly address any abnormalities.
Interventions are coordinated with project leaders and veterinarians to ensure proper care.
The Center for Translational Medicine\u2019s Animal Welfare Body oversees
as required\nby Article 25 of the Act.
This team monitors research, reviews protocols,
and supports scientists in\nimplementing
best experimental practices while ensuring the highest level of animal welfare.
The facility holds official authorization from the District Veterinary Officer
to conduct research on animals.
Furthermore, it offers comprehensive support in preparing project documentation
and ethical approval\napplications,
facilitating compliance with current legal and scientific standards.<\/p>\n\n\n\n
The Small Animal Models Laboratory offers extensive opportunities
for collaboration in scientific,\ndevelopment,
and preclinical projects. The facility provides full support for academic institutions, research\norganizations,
and the biomedical industry, including:
Maintenance of small animal models (mice, rats, guinea pigs)
in strictly controlled environments with\ncomprehensive veterinary care
and post-operative recovery support,
Development of human disease models,
including metabolic (e.g. diabetes), neurological, oncological,\ninflammatory,
and immunological conditions, using standardized and customized animal models,
Conducting toxicological, pharmacokinetic, pharmacodynamic, and safety and efficacy studies
of\nnew biologically active substances
and drug candidates,
Research on tissue regeneration, wound healing, biomaterial integration, and immune response
analysis under
controlled conditions,<\/p>\n\n\n\n
considering species, sex,\nage, strain, and other biological features,
\u2022 Supervision of animal welfare and maintenance
of quality control documentation in accordance
with\napplicable laws and the 3Rs principle,
\u2022 Support in preparing documentation for animal research protocols
and submissions to
the Local\nEthical Committee.<\/p>\n\n\n\n
infrastructure, including the Imaging Unit (X-ray, luminescence, two-photon microscopy),
surgical facilities,\nand the Histology,
Microbiology, Molecular Biology, and Cytometry Laboratories.
This comprehensive\napproach enables the execution of complex research projects \u2014
from model development to final data\nanalysis and publication.<\/p>\n\n\n\n
Animal Research Coordinator
Prof. Romuald Zabielski, DVM, PhD\nromuald_zabielski@sggw.edu.pl
\u2022 CMT Secretariat:
cmt@sggw.edu.pl; tel: +48 22 593 38 40<\/p>","protected":false},"excerpt":{"rendered":"